777 research outputs found

    Influence of Rice Production on the Quality of Water in Tailwater Collection Reservoirs

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    Since maintaining high water quality standards in the state remains a high priority, monitoring for pesticides in water sources must continue. Determining the type, concentration, and characteristics of any pesticides present in water supplies are essential to the overall assessment of water quality. Five independent locations, implementing contained water management systems and recyclable water, were monitored in 1995 and 1996. Irrigation, runoff, and pond water samples were collected every 10 to 14 days between permanent flood establishment and draining. Water samples were transported to the laboratory and extracted for 16 pesticides using solid phase extraction (SPE) techniques. Quantification and confirmation of pesticide residues were obta1ned by HPLC and GC/MS analysis. The lower limit of quantitation for all pesticides was between 1.0 -1.3 pg L-1 in water. Pesticides selected for monitoring were determined after assessing state recommendations and our analytical capabilities. Pesticides included: benomyl, bensulfuron methyl, carbaryl, carbofuran, 2,4-D, fenoxaprop ethyl, propiconazole, malathion, MCPA, methyl parathion, molinate, pendimethalin, propanil, iprodione, quinclorac, triclopyr, and thiobencarb. Since each field location was independently managed, individual results are site specific. 2,4-D, benomyl, molinate, propanil, quinclorac, thiobencarb, and pendimethalin were the pesticides actually applied during the seasons. These pesticides were detected, usually at trace levels, in tailwaters shortly after application but did not appear to buildup in the reservoirs. Quinclorac residues in the tailwaters were more persistent (up to 8 weeks) than the other detected compounds (less than 2 weeks)

    Determining Pesticide and Nitrate Levels in Spring Water in Northwest Arkansas

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    Occurrences of pesticides in our nations ground water are on the rise. As states become aware of this problem and begin monitoring programs, incidence of contamination will probably increase. Since the problem of pesticides in groundwater is relatively new, little research has centered on the fate of pesticides after they reach the groundwater environment. In Northwest Arkansas efforts to monitor groundwater for pesticides have been small. Twenty-five springs in Northwest Arkansas were sampled in the fall of 1988, and spring of 1989. Analysis for atrazine, alachlor, metolachlor, diuron, and simazine in spring water was preformed using gas liquid chromatography and high performance liquid chromatography. No detectable residues of any of the selected pesticides were found. Northwest Arkansas is a leader in poultry production. Much of the manure from poultry houses is spread on the sourounding pastures. As this litter decomposes nitrates and phosphates are released. Nitrate and phosphate concentrations were also determined on water from the spring samples. No spring exceeded the EPA\u27s limit of 45 mg/L for nitrate in drinking water. The highest concentration for phosphate in any spring was 1.05 mg/L

    Foreign Body Extraction Device

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    Foreign bodies in the gastrointestinal tract are common. Mostly they are swallowed accidentally by children but also by adults. When round and slippery, foreign bodies cause a technical problem for removal. After several days in the stomach they are covered with mucus and extraction becomes even harder. There are various devices designed for use through the flexible endoscope for grasping foreign bodies but due to the great variety of objects, one may face a real problem while trying to remove them. We faced a challenge in a woman who underwent vertical band gastroplasty and was obstructed by a round and slippery hazelnut. We managed to remove the nut using a simple homemade device. This device is easy to make, cheap, and simple to use and maybe useful for various foreign bodies

    Geographical Differences in the Forefoot Morphology – A Comparative Radiological Study of Feet in Malawi and UK

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    Background: Many skeletal morphological differences between populations have been reported with possible but unproven clinical importance. This study was aimed at identifying the normal radiographic findings and measurements seen in patients from Southern Africa and compares them to a European population’s values.Methods: AP foot radiographs of 40 adults from Blantyre, Malawi were compared with those of 40 adults from London, UK. For each patient, measurements were taken of: 1st and 2nd metatarsal lengths, the 1st/2nd intermetatarsal angle, the 1st metatarso- phalangeal angle (the ‘bunion’ angle), and the 2nd metatarsal mortice joint medial and lateral depths.Results: Our results show an increased 1st/2nd metatarsal angle in Malawian feet, but a reduced ‘bunion’ angle. We also found the second metatarsal length to be longer relative to the first in the Malawian foot, and the 2nd metatarsal base to be significantly more covered by its mortice than in UK feet.Conclusion: This racial anatomical variation may convey more stability and less risk of a Lisfranc dislocation. It is also important to be aware of the normal range of these values when considering the need for forefoot arthroplasty procedures

    Macroeconomic costs of the unmet burden of surgical disease in Sierra Leone: a retrospective economic analysis.

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    OBJECTIVES: The Lancet Commission on Global Surgery estimated that low/middle-income countries will lose an estimated cumulative loss of US12.3 trillionfromgrossdomesticproduct(GDP)duetotheunmetburdenofsurgicaldisease.However,nocountry−specificdatacurrentlyexist.WeaimedtoestimatethecoststotheSierraLeoneeconomyfromdeathanddisabilitywhichmayhavebeenavertedbysurgicalcare.DESIGN:Weusedestimatesoftotal,metandunmetneedfromtwomainsources−aclusterrandomised,cross−sectional,countrywidesurveyandaretrospective,nationwidestudyonsurgeryinSierraLeone.Wecalculatedestimateddisability−adjustedlifeyearsfrommorbidityandmortalityfortheestimatedunmetburdenandmodelledthelikelyeconomicimpactusingthreedifferentmethods−grossnationalincomepercapita,lifetimeearningsforegoneandvalueofastatisticallife.RESULTS:In2012,estimated,discountedlifetimelossestotheSierraLeoneeconomyfromtheunmetburdenofsurgicaldiseasewasbetweenUS12.3 trillion from gross domestic product (GDP) due to the unmet burden of surgical disease. However, no country-specific data currently exist. We aimed to estimate the costs to the Sierra Leone economy from death and disability which may have been averted by surgical care. DESIGN: We used estimates of total, met and unmet need from two main sources-a cluster randomised, cross-sectional, countrywide survey and a retrospective, nationwide study on surgery in Sierra Leone. We calculated estimated disability-adjusted life years from morbidity and mortality for the estimated unmet burden and modelled the likely economic impact using three different methods-gross national income per capita, lifetime earnings foregone and value of a statistical life. RESULTS: In 2012, estimated, discounted lifetime losses to the Sierra Leone economy from the unmet burden of surgical disease was between US1.1 and US3.8 billion,dependingontheeconomicmethodused.Theselifetimelossesequatetobetween233.8 billion, depending on the economic method used. These lifetime losses equate to between 23% and 100% of the annual GDP for Sierra Leone. 80% of economic losses were due to mortality. The incremental losses averted by scale up of surgical provision to the Lancet Commission target of 80% were calculated to be between US360 million and US$2.9 billion. CONCLUSION: There is a large economic loss from the unmet need for surgical care in Sierra Leone. There is an immediate need for massive investment to counteract ongoing economic losses

    A simple method to assess the oxidative susceptibility of low density lipoproteins

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    BACKGROUND: Oxidative modification of low density lipoproteins (LDL) is recognized as one of the major processes involved in atherogenesis. The in vitro standardized measurement of LDL oxidative susceptibility could thus be of clinical significance. The aim of the present study was to establish a method which would allow the evaluation of oxidative susceptibility of LDL in the general clinical laboratory. RESULTS: LDL was isolated from human plasma by selective precipitation with amphipathic polymers. The ability of LDL to form peroxides was assessed by measuring thiobarbituric acid reactive substances (TBARS) after incubation with Cu(2+) and H(2)O(2). Reaction kinetics showed a three-phase pattern (latency, propagation and decomposition phases) which allowed us to select 150 min as the time point to stop the incubation by cooling and EDTA addition. The mixture Cu(2+)/H(2)O(2) yielded more lipoperoxides than each one on its own at the same time end-point. Induced peroxidation was measured in normal subjects and in type 2 diabetic patients. In the control group, results were 21.7 ± 1.5 nmol MDA/mg LDL protein, while in the diabetic group results were significantly increased (39.0 ± 3.0 nmol MDA/mg LDL protein; p < 0.001). CONCLUSION: a simple and useful method is presented for the routine determination of LDL susceptibility to peroxidation in a clinical laboratory

    Barriers to women entering surgical careers: a global study into medical student perceptions

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    Background Barriers to female surgeons entering the field are well documented in Australia, the USA and the UK, but how generalizable these problems are to other regions remains unknown. Methods A cross-sectional survey was developed by the International Federation of Medical Students' Associations (IFMSA)'s Global Surgery Working Group assessing medical students' desire to pursue a surgical career at different stages of their medical degree. The questionnaire also included questions on students' perceptions of their education, resources and professional life. The survey was distributed via IFMSA mailing lists, conferences and social media. Univariate analysis was performed, and statistically significant exposures were added to a multivariate model. This model was then tested in male and female medical students, before a further subset analysis by country World Bank income strata. Results 639 medical students from 75 countries completed the survey. Mentorship [OR 3.42 (CI 2.29–5.12) p = 0.00], the acute element of the surgical specialties [OR 2.22 (CI 1.49–3.29) p = 0.00], academic competitiveness [OR 1.61 (CI 1.07–2.42) p = 0.02] and being from a high or upper-middle-income country (HIC and UMIC) [OR 1.56 (CI 1.021–2.369) p = 0.04] all increased likelihood to be considering a surgical career, whereas perceived access to postgraduate training [OR 0.63 (CI 0.417–0.943) p = 0.03], increased year of study [OR 0.68 (CI 0.57–0.81) p = 0.00] and perceived heavy workload [OR 0.47 (CI 0.31–0.73) p = 0.00] all decreased likelihood to consider a surgical career. Perceived quality of surgical teaching and quality of surgical services in country overall did not affect students' decision to pursue surgery. On subset analysis, perceived poor access to postgraduate training made women 60% less likely to consider a surgical career [OR 0.381 (CI 0.217–0.671) p = 0.00], whilst not showing an effect in the men [OR 1.13 (CI 0.61–2.12) p = 0.70. Concerns about high cost of training halve the likelihood of students from low and low-middle-income countries (LICs and LMICs) considering a surgical career [OR 0.45 (CI 0.25–0.82) p = 0.00] whilst not demonstrating a significant relationship in HIC or UMIC countries. Women from LICs and LMICs were 40% less likely to consider surgical careers than men, when controlling for other factors [OR 0.59 CI (0.342–1.01 p = 0.053]. Conclusion Perceived poor access to postgraduate training and heavy workload dissuade students worldwide from considering surgical careers. Postgraduate training in particular appears to be most significant for women and cost of training an additional factor in both women and men from LMICs and LICs. Mentorship remains an important and modifiable factor in influencing student's decision to pursue surgery. Quality of surgical education showed no effect on student decision-making

    Paradoxical effects of Worrisome Thoughts Suppression: the influence of depressive mood

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    Thought suppression increases the persistence of unwanted idiosyncratic worries thoughts when individuals try to suppress them. The failure of suppression may contribute to the development and maintenance of emotional disorders. Depressive people seem particulary prone to engage in unsuccessful mental control strategies such as thought suppression. Worry has been reported to be elevated in depressed individuals and a dysphoric mood may also contribute for the failure of suppression. No studies examine, however, the suppression of worisome thoughts in individuals with depressive symptoms. To investigate the suppression effects of worrisome thoughts, 46 participants were selected according to the cut-off score of a depressive symptomatology scale and they were divided in two groups (subclinical and nonclinical group). All the individuals took part in an experimental paradigm of thought suppression. The results of the mixed factorial analysis of variance revealed an increased frequency of worrisome thoughts during the suppression phase on depending of the depressive symptoms. These findings confirm that depressive mood can reduce the success of suppression.info:eu-repo/semantics/publishedVersio

    Efficacy of a combination of imidacloprid 10%/moxidectin 2.5% spot-on (Advocate® for dogs) in the prevention of canine spirocercosis (Spirocerca lupi)

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    The nematode Spirocerca lupi is a major canine parasite in warm regions of the world, classically causing parasitic nodules in the esophagus, aortic aneurysms, and spondylitis. This study evaluated the preventive efficacy of monthly treatment with imidacloprid 10%/moxidectin 2.5% spot-on (Advocate® for dogs) administered over a period of 9 months in young dogs naturally exposed to S. lupi on Réunion island. One hundred and twelve puppies, aged from 2.0 to 4.0 months and with a negative spirocerca fecal examination at inclusion, completed the study. They were randomly allocated to two groups. Group A puppies (n = 58) received nine spot-on treatments with Advocate® at the minimum dose of 2.5 mg moxidectin/kg bw at monthly intervals. Control group B puppies (n = 54) received no treatment for S. lupi. During the study, regular clinical and fecal examinations were performed, as was final upper gastrointestinal endoscopy. Endoscopy showed that 19 dogs from group B had spirocerca nodules, corresponding to a prevalence of 35.2% in dogs aged 12 to 14 months. In contrast, only one dog from group A had a nodule, corresponding to a preventive efficacy of 94.7% (p < 0.0001). None of the 378 fecal examinations were positive for spirocerca. This study confirms a high prevalence of canine spirocercosis on Réunion and shows that infestation occurs in very young puppies. Furthermore, it demonstrates that monthly spot-on administration of a combination of imidacloprid 10%/moxidectin 2.5% (Advocate® for dogs) in puppies starting at the age of 2 to 4 months achieves effective and safe prevention of canine spirocercosis
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